One of the most difficult issues in dealing with depression is the issue of medications and potential side effects. Antidepressants can have different effects on sleep, changes in weight, sexual functioning, and in how they impact you when you stop taking them.
Some prescriptions are more expensive than others, which can mean a higher insurance copay. Some have fancy names with commercials that suggest they can cure you without any fuss. Add to this the myriad of different choices, different mechanisms of action (SSRI, SNRI, Tricyclic, and so on) and multiple (brand vs. generic) names, and it’s enough to tear your hair out.
The Mayo Clinic published a Depression Decision Worksheet, which can help you to navigate through all the ins and outs of some of the more commonly used medications. It’s worth consulting if you want to be well informed in having a dialogue with your psychiatrist, nurse practitioner, or PCP. While the chart gets updated on a regular basis, you can find a copy of the one current as of this writing (Jan 2018) here: Medication for Depression Decision Aid